Reducing the Duration of Untreated Psychosis in the United States (R01 Clinical Trial Required) | PAR 18 233

Opportunity Information: Apply for PAR 18 233

The government grant opportunity titled "Reducing the Duration of Untreated Psychosis in the United States" aims to address the pressing issue of untreated psychosis among adolescents and young adults. Each year, around 100,000 individuals in this age group experience their first episode of psychosis, and early intervention is crucial for improving outcomes related to schizophrenia and similar disorders. Research shows that integrated treatment programs, known as Coordinated Specialty Care (CSC), which combine medications, psychological support, and rehabilitation, lead to better clinical and functional results compared to traditional treatments.

A significant challenge noted in the U.S. is the considerable delay—often one to three years—between the onset of psychotic symptoms and the beginning of treatment. This delay can have serious consequences, including functional deterioration. The World Health Organization recommends reducing the duration of untreated psychosis (DUP) to three months or less. To achieve this, the Funding Opportunity Announcement (FOA) encourages research projects that explore practical strategies to shorten DUP by improving access to CSC services and addressing obstacles that hinder timely treatment.

Eligible applicants for this grant include various educational and community institutions, such as historically black colleges, Hispanic-serving institutions, and tribal colleges. However, foreign entities are not eligible to apply, although foreign components within U.S. organizations can participate. The goal is to foster research that effectively reduces treatment delays for those experiencing their first episode of psychosis.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Reducing the Duration of Untreated Psychosis in the United States (R01 Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
• This funding opportunity was created on 2017-11-21.
• Applicants must submit their applications by 2019-03-19. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2025.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 18 233

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